Minggu, 23 Januari 2022

Former Malaysian PM Mahathir in stable condition in hospital - Reuters

KUALA LUMPUR, Jan 22 (Reuters) - Malaysia's former prime minister Mahathir Mohamad is in a stable condition after undergoing treatment at the National Heart Institute, his daughter said in a statement on Saturday.

Marina Mahathir said her 96-year-old father had been readmitted to hospital and has undergone two days of treatment following an elective medical procedure in early January.

"Siti Hasmah Mohd Ali (his wife) and family ask for the people to pray for his speedy and full recovery," Marina said.

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A spokesperson for Mahathir earlier said he was admitted to the cardiac care unit at the hospital but gave no details.

Mahathir, who is still an active lawmaker, had been discharged from hospital after what was described as an successful elective medical procedure on Jan.8.

The National Heart Institute did not say at the time what procedure Mahathir, who has a history of heart problems, had undergone.

In December, he was admitted and discharged after his doctors said they were satisfied with the results of necessary investigations.

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Reporting by Liz Lee; Editing William Mallard and Ros Russell

Our Standards: The Thomson Reuters Trust Principles.

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2022-01-22 11:38:00Z
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Sabtu, 22 Januari 2022

Meat Loaf, singer of I'd Do Anything For Love (But I Won't Do That), dies aged 74 - CNA

Meat Loaf, the singer best known for the Bat Out Of Hell album and the hit song I’d Do Anything For Love (But I Won’t Do That), has died at the age of 74, a statement on his official Facebook page said on Friday (Jan 21).

No cause of death was revealed.

The American singer and actor, otherwise known as Michael Lee Aday, had a career spanning six decades, and sold more than 100 million albums worldwide.

His family said in a statement: “We know how much he meant to so many of you and we truly appreciate all of the love and support as we move through this time of grief in losing such an inspiring artist and beautiful man. From his heart to your souls…don’t ever stop rocking!”

The singer was known for the bestselling album trilogy, Bat Out Of Hell. The second album, Bat Out Of Hell II: Back Into Hell yielded the hit song, I’d Do Anything For Love (But I Won’t Do That).

Aday died on Thursday (Jan 20) night with his wife by his side, according to Deadline, citing his longtime agent Michael Greene.

Greene also told the publication that the singer’s daughters, Pearl and Amanda, as well as close friends had a chance to spend time with him and say their goodbyes.

BAT OUT OF HELL

His first Bat Out Of Hell album came out in 1977, a mega-selling collaboration with songwriter Jim Steinman and producer Todd Rundgren that made him one of the most recognisable performers in rock.

Fans fell hard for the roaring vocals of the long-haired, 250-plus pound singer and for the comic non-romance of the title track, You Took The Words Right Out Of My Mouth, Two Out Of Three Ain’t Bad and Paradise By The Dashboard Light, an operatic cautionary tale about going all the way.

After a slow start and mixed reviews, Bat Out Of Hell became one of the top-selling albums in history, with worldwide sales of more than 40 million copies.

Meat Loaf wasn’t a consistent hit maker, especially after falling out for years with Steinman. But he maintained close ties with his fans through his manic live shows, social media and his many television, radio and film appearances, including Fight Club and cameos on Glee and South Park.

His biggest musical success after Bat Out Of Hell was Bat Out Of Hell II: Back Into Hell, a 1993 reunion with Steinman that sold more than 15 million copies and featured the Grammy-winning single I’d Do Anything for Love (But I Won’t Do That).

ORIGINS OF ‘MEAT LOAF’

A native of Dallas, Aday was the son of a school teacher who raised him on her own after divorcing his alcoholic father, a police officer. Aday was singing and acting in high school (Mick Jagger was an early favorite, so was Ethel Merman) and attended Lubbock Christian College and what is now the University of North Texas. Among his more notable childhood memories: Seeing John F. Kennedy arrive at Love Field in Dallas on Nov. 22, 1963, then learning the president had been assassinated and driving to Parkland Hospital and watching a bloodied Jackie Kennedy step out of a car.

He was still a teenager when his mother died and when he acquired the nickname Meat Loaf, the alleged origins of which range from his weight to a favorite recipe of his mother’s. He left for Los Angeles after college and was soon fronting the band Meat Loaf Soul. For years, he alternated between music and the stage, recording briefly for Motown, opening for such acts as the Who and the Grateful Dead and appearing in the Broadway production of Hair.

By the mid-1970s, he was playing the lobotomised biker Eddie in the theater and film versions of The Rocky Horror Picture Show, had served as an understudy for his friend John Belushi for the stage production of National Lampoon and had begun working with Steinman on Bat Out Of Hell.

The album took more than two years to find a taker as numerous record executives turned it down, including RCA’s Clive Davis, who disparaged Steinman’s songs and acknowledged that he had misjudged the singer: “The songs were coming over as very theatrical, and Meat Loaf, despite a powerful voice, just didn’t look like a star,” Davis wrote in his memoir, “The Soundtrack of My Life.”

‘THESE PEOPLE THINK WE’RE SERVING DINNER’

With the help of another Springsteen sideman, Steve Van Zandt, Bat Out Of Hell was acquired by Cleveland International, a subsidiary of Epic Records. The album made little impact until months after its release, when a concert video of the title track was aired on the British program the Old Grey Whistle Test. In the US, his connection to Rocky Horror helped when he convinced producer Lou Adler to use a video for Paradise By The Dashboard Light as a trailer for the cult movie. But Meat Loaf was so little known at first that he began his Bat Out Of Hell tour in Chicago as the opening act for Cheap Track, then one of the world’s hottest groups.

“I remember pulling up at the theater and it says, ‘TONIGHT: CHEAP TRICK, WITH MEAT LOAF.’ And I said to myself, ‘These people think we’re serving dinner,’” Meat Loaf explained in 2013 on the syndicated radio show In the Studio.

“And we walk out on stage and these people were such Cheap Trick fans they booed us from the start. They were getting up and giving us the finger. The first six rows stood up and screamed. ... When we finished, most of the boos had stopped and we were almost getting applause.”

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2022-01-21 08:23:00Z
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China's Harbin to conduct city-wide COVID-19 tests ahead of Chinese New Year holiday - CNA

Many cities have advised residents to stay put or requiring travellers to report their trips days before their arrival.

Still, some state media outlets are warning against being too harsh, after a county-level government official in Henan province was quoted as saying that some people had ignored the advice to "maliciously return" to their hometown and that they would quarantine and detain such cases.

"It is human nature to return home during the Spring Festival for reunions, so why is it malicious?," the official People's Daily newspaper said on its Weibo account.

"Preventing and controlling the epidemic is a big task, but we cannot take a one size fits all approach...(it) must be done in a scientific and legal way, and every desire to return home must be treated compassionately."

Mainland China reported 63 new COVID-19 cases on Jan 21, down from 73 cases a day earlier, the country's national health authority said on Saturday.

The National Health Commission said in a statement that 23 of the new cases were locally transmitted, the same as a day earlier, and the rest imported.

The number of new asymptomatic cases, which China does not classify as confirmed cases, rose to 43 from 31 a day earlier.

There were no new deaths, leaving the death toll at 4,636.

As of Jan 21, mainland China had 105,547 confirmed cases.

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2022-01-22 05:19:00Z
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Jumat, 21 Januari 2022

Booster vaccine programme to be extended to persons aged 12 to 17 in Singapore - Yahoo Singapore News

covid-19 coronavirus booster vaccination concept

COVID-19 booster vaccination. (PHOTO: Getty Images)

SINGAPORE — From early next month, the booster vaccination programme will be extended to those aged 12 to 17 years old, the multi-ministerial taskforce on COVID-19 said on Friday (21 January).

The extended programme will start with those aged 16 and 17 years, followed by those aged 12 to 15 years.

All those between the age of 12 to 17 years will require the consent of their parent or guardian to book an appointment. Parents or guardians will receive an SMS with a personalised booking link to the mobile number that they have registered with for the primary series, to provide consent and book their child or ward’s booster vaccination appointment. 

They can be boosted in any vaccination centre offering the Pfizer- BioNTech/Comirnaty vaccine and should bring the personal identification of their child or ward for verification.

Parents or guardians of children or wards aged 13 and above are not required to accompany them on the day of vaccination. However, children or wards aged 12 and students in Special Education (SPED) schools will need to be accompanied by a parent or guardian. The authorities will work with SPED schools, and more details will be shared at a later date.

Individuals aged 12 to 17 years who are medically ineligible for the Pfizer- BioNTech/Comirnaty vaccine will be offered a Sinovac-CoronaVac booster dose. This will also be extended to children aged 5 to 11 years who are medically ineligible for the Pfizer-BioNTech/Comirnaty vaccine for their primary vaccination series.

Consequently, the requirement for the fully vaccinated status will be amended for this age group.

Previously, the authorities announced that from 14 February, persons aged 18 years and above who have completed the primary vaccination series and are eligible for booster vaccination will be considered as fully vaccinated for only 270 days after the last dose in their primary vaccination series. Upon receiving their booster, they will continue to maintain their vaccinated status.

Starting from 14 March, persons aged 12 to 17 years who have completed their primary series and are now eligible for booster vaccination will also be considered fully vaccinated for only 270 days after their last primary series dose, and will require a booster dose to maintain their vaccinated status thereafter.

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2022-01-21 08:09:42Z
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Children aged 12 to 17 must get COVID-19 booster within 270 days of 2nd dose to maintain fully vaccinated status - CNA

SINGAPORE: From March 14, those aged between 12 and 17 will need to get a booster shot within 270 days of receiving their second dose of the COVID-19 vaccine, in order to maintain their fully vaccinated status, announced the Ministry of Health (MOH) on Friday (Jan 21). 

The extension of the booster programme to this age group comes on the recommendations of the Expert Committee on COVID-19 Vaccination (EC19V), MOH added.

Currently, only those aged 18 years and above are offered a booster dose of an mRNA vaccine, under the National Vaccination Programme, five months after completing their primary vaccination series.

This group will be required to take a booster shot within 270 days of completing their primary vaccination series in order to maintain a fully vaccinated status against COVID-19 from Feb 14.

In a news release on Friday, MOH said that the COVID-19 booster vaccination programme will be progressively extended to those aged between 12 and 17 from early February.

It will start with those who are 16 or 17 years old, followed by those aged between 12 and 15.

"Vaccinations, especially boosters, will ensure we retain substantial protection against Omicron," said MOH.

"Boosters have helped dampen the rise in Omicron cases thus far and increases our protection against infection and severe illness."

SAFETY CONCERNS

At a press conference by the COVID-19 multi-ministry taskforce on Friday, MOH’s director of medical services Kenneth Mak addressed safety concerns over booster shots for this age group.

"The experience in Israel, the US and the UK has shown that adolescents are as vulnerable to breakthrough infections following vaccination, as in adults. But the booster vaccinations have been shown to increase the protection back against the Omicron variant," he said.

"Local and international data has shown that the safety profile and side effects for the booster dose is compatible with that for the first two doses and with a significantly lower myocarditis risk," he added.

Asked if a booster shot would eventually be required for children under 12 years old, Assoc Prof Mak said that "there are no plans at this stage".

"We will monitor the situation closely to see if, as in other age groups, the vaccine protection wanes over time, and whether it leads to an increased vulnerability to breakthrough infections arising particularly in the setting of other viral variants that may emerge in the future," he added.

"And at that point in time, we will make recommendations guided by EC19V on whether booster vaccinations are then required for this age group, as in the other age groups."

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2022-01-21 08:08:00Z
1256844941

Kamis, 20 Januari 2022

Merck COVID-19 pill molnupiravir to be produced by 27 drugmakers - CNA

BRUSSELS: A UN-backed agency has struck a deal for nearly 30 generic drugmakers to make low-cost versions of Merck & Co's COVID-19 pill molnupiravir for poorer nations, widening access to a drug seen as a weapon in fighting the pandemic.

The antiviral pill, which in December received emergency approval in the United States, reduces hospitalisations and deaths of high-risk patients by around 30 per cent, according to clinical trial results.

The deal, negotiated by the UN-backed Medicines Patent Pool (MPP) with Merck, will expand output by increasing the number of companies that will produce the drug, after Merck entered into licensing agreements with eight Indian drugmakers in October.

The new agreement allows 27 generic drugmakers from India, China and other countries in Africa, Asia and the Middle East to produce ingredients and the finished drug.

The MPP said the deal stipulated the pill would be distributed to 105 less-developed nations. A spokesperson later said deliveries from some firms covered by the deal could start as early as February.

A molnupiravir course of 40 pills for five days is expected to cost about US$20 in poorer nations, an MPP official involved in the talks with drugmakers told Reuters, citing initial estimates from drugmakers, which are subject to change.

That is far below the US$700 per course the United States agreed to pay for an initial delivery of 1.7 million courses, but twice as high as first estimated by the World Health Organization (WHO)-backed programme to procure COVID-19 drugs and vaccines for the world.

NO ROYALTIES, FOR NOW

The developers of molnupiravir, which alongside Merck are US firm Ridgeback Biotherapeutics and Emory University, will not receive royalties for the sale of the low-cost versions made by generic drugmakers while COVID-19 remains classified as a Public Health Emergency of International Concern by the WHO.

Bangladesh's Beximco Pharmaceuticals, India's Natco Pharma, South Africa's Aspen Pharmacare Holdings and China's Fosun Pharma are among generics firms that will produce the finished product.

Other companies, including India's Dr Reddy's Laboratories , had struck earlier deals with Merck for the production of molnupiravir. Dr Reddy's will sell molnupiravir at 1,400 rupees (US$18.8) per course.

The MPP spokesperson said there was no firm estimate yet of the likely output from generics makers covered by the deal, but that poorer nations' demand was expected to be largely covered.

The MPP works to increase access to life-saving medicines for poorer countries. It also has an agreement with Pfizer for the sub-licensing of its COVID-19 pill paxlovid to generic drugmakers.

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2022-01-20 09:46:26Z
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Endemic COVID-19: What would that mean? - CNA

Two years into the pandemic, weary governments are hoping the fast-spreading but less severe Omicron variant marks a turning point, a shift toward a more predictable and manageable phase.

Determined to escape the crisis and avoid more restrictions, officials in some countries suggest it is approaching time to treat COVID-19 as an endemic disease, like seasonal flu. World Health Organization (WHO) experts say that is premature.

With Omicron ripping through populations and vast parts of the planet still unvaccinated, the pandemic is not over. The bottom line: The path to reaching that endemic stage is full of uncertainties, posing tough questions for policymakers everywhere.

WHAT DOES ENDEMIC MEAN?

In an epidemic, a disease spreads rapidly and unexpectedly in a given location; it becomes a pandemic when it spreads globally, or over a very wide area.

A disease that is endemic is continuously present in a given population at a lower and more stable level, even if cases spike under certain conditions.

Scientists expect that when enough people gain at least some protection from the coronavirus through vaccines or prior infections, it will blunt the spread of the virus and reduce hospitalisations and deaths, so that over time COVID-19 will pose less of a threat.

The virus will not go away entirely, however, and endemic diseases can still take a serious toll. Tuberculosis and malaria, which are endemic in some parts of the world, claimed an estimated 1.5 million and 627,000 lives, respectively, in 2020.

“Endemic in itself does not mean good. Endemic just means it’s here forever,” said Mike Ryan, executive director of the WHO’s health emergencies programme.

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2022-01-20 09:41:32Z
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